Nfl Week 6 Predictions 2025. Get the latest 2025 nfl week 6 odds with current lines, point spreads, moneylines, totals, line movement and a breakdown of every week 6 nfl game. The san francisco 49ers and.

Detroit’s offensive line is legit, and the lions have tons of weapons that will get open if given time. Our expert nfl handicappers research the entire nfl week 6.